Clindax-B Gel

Indications of Clindax-B 20 Topical Gel

A combination of medications called Clindax-B is used to treat acne. It eliminates acne-causing bacteria. Additionally, it replenishes the skin and lowers oil production. You should take Clindax-B for the recommended amount of time and dosage.

Pharmacology of Clindax-B 20 Topical Gel

A semi-synthetic lincomycin derivative is a clindamycin. By reversibly binding to the 50S ribosomal subunits, it prevents sensitive organisms from transpeptiding or translocating and reduces bacterial protein synthesis.

Benzoyl peroxide has a modest keratolytic and antibacterial effect due to its strong oxidizing activity. Both clindamycin and benzoyl peroxide works well against the Propionibacterium acnes bacteria, which is the root cause of acne vulgaris.

Dosage & Administration of Clindax-B 20 Topical Gel

• Apply to the affected areas once or twice daily (morning and evening) after the skin is gently washed and patted dry.

Interaction of Clindax-B 20 Topical Gel

It might make neuromuscular blockers function more effectively (e.g. atracurium). It’s possible that it will negate parasympathomimetics’ effects. It’s possible that linezolid, chloramphenicol, streptogramins, macrolides, and ketolides will vie for your attention. Increased coagulation tests (prothrombin time/INR) and/or bleeding can happen when using vitamin K antagonists (e.g. warfarin, acenocoumarol, fluindione). The cloth may temporarily turn discolored as a result of PABA sunscreens.

Contraindications

History of regional enteritis, ulcerative colitis, pseudomembranous colitis, or antibiotic-associated colitis; hypersensitivity to Clindamycin, lincomycin, benzoyl peroxide, or any other component of the formulation.

Side Effects of Clindax-B 20 Topical Gel

• Skin peeling
• Dry skin
• Erythema (skin redness)
• Burning sensation at the site of application
   

Pregnancy & Lactation

C is the pregnancy category. Animal reproduction studies have revealed an unfavorable effect on the fetus and there are no adequate and well-controlled studies in humans, however, potential advantages may support the use of the medicine in pregnant women despite potential concerns

Lactation: Milk excretion is unknown/not advised.

Precautions & Warnings

Avoid contact with abraded or eczematous skin, as well as the mouth, eyes, lips, and mucous membranes. Hair and colorful textiles may be discolored. Lactation and pregnancy.

Storage Conditions

Store in a cool and dry place, away from light and children.