Adaben Duo Gel

Indications of Adaben Duo 20

Adaben Duo Gel is a prescription medicine that contains a combination of medications used to treat acne in patients aged 12 and up. It removes the dead layer of skin on top of the skin. It inhibits bacterial growth. Adaben Duo Gel should be taken in the dose and for the duration prescribed by your doctor.

Pharmacology

Adaben Duo 20 gel is approved for the topical treatment of acne vulgaris in patients aged 12 and up. Adapalene binds to nuclear retinoic acid receptors but not to cytosolic receptor protein. Adapalene is a modulator of cellular differentiation, keratinization, and inflammatory processes, according to biochemical and pharmacological profile studies. Adapalene binds to specific retinoic acid nuclear receptors, which normalizes follicular epithelial cell differentiation, resulting in decreased microcomedone formation. Benzoyl peroxide is a bacteriocidal and keratolytic oxidizing agent.

Dosage & Administration of Adaben Duo 20

• It is advised to check the label for directions before use.
• Apply a thin film of Adapalene & Benzoyl peroxide gel to affected areas of the face and/or trunk once daily after washing.
• Use a pea-sized amount for each area of the face (e.g., forehead, chin, each cheek).
• Avoid the eyes, lips, and mucous membranes. Adapalene & Benzoyl peroxide is not for oral, ophthalmic, or intravaginal use.
• Do not apply to broken, sunburnt, or sensitive areas of skin. Inform your doctor if you notice unusual dryness, redness, and peeling of the skin.
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• Be careful when applying Adaben Duo Gel to large areas since it can bleach hair, clothing, and furnishings upon contact.
• Inform your doctor if you are pregnant, planning pregnancy, and breastfeeding.

Interaction of Adaben Duo 20

Concomitant topical acne therapy should be used with caution because a possible cumulative irritancy effect may occur, especially with the use of peeling, desquamating, or abrasive agents. No formal drug-drug interaction studies were conducted.

Contraindications

Should not be administered to individuals who are hypersensitive to any of its components.

Side Effects of Adaben Duo 20

• Erythema (skin redness)
• Skin peeling
• Skin irritation
• Dry skin
• Burning/Stinging sensation at the site of application
• Erythema
• Scaling

Pregnancy & Lactation

There are no well-controlled trials in pregnant women treated with Adapalene and Benzoyl peroxide. Animal reproduction studies have not been conducted with the combination gel or Benzoyl peroxide. Furthermore, such studies are not always predictive of human response; therefore, this preparation should be used during pregnancy only if the potential benefit justifies the risk to the fetus. It is not known whether Adapalene or Benzoyl peroxide is excreted in human milk following use. Caution should be exercised when administered to a nursing woman.

Precautions & Warnings

Avoid exposure to sunlight and sunlamps. Wear sunscreen when sun exposure cannot be avoided.

Storage Conditions

Store in a cool (below 25?C) and dry place protected from light and moisture. Keep out of the reach of children. Keep the tube tightly closed after use.