Clofenac Gel

Description:

Indications of Clofenac Gel 20gm Clofenac Gel is indicated forRheumatology includes inflammatory and degenerative conditions such as chronic involutive rheumatism, polyarthritis, ankylosing spondylarthritis, osteoarthritis, spondylarthritis, acute gout, and peri-articular rheumatic diseases.Sprains, bruises, dislocations, fractures, soft tissue injuries, and surgical interventions are all treated in surgery and traumatology.Obstetrics and Gynecology: Primary dysmenorrhea, episiotomy, adnexitis, endometritis, parametritis, salpingitis, and mastitis.Pre-operative medication for the prevention of pain, inflammation, and swelling in otorhinolaryngology.Post-operative and post-traumatic pain, inflammation, and swelling in dentistry.Other indications include the prevention of pain and the treatment of inflammation and swelling in patients undergoing urogenital tract, renal, and biliary colic surgery.Pharmacology of Clofenac Gel 20gmDiclofenac Sodium is a nonsteroidal anti-inflammatory medication that is anti-rheumatic, anti-inflammatory, analgesic, and antipyretic (NSAID). It has uricosuric properties as well. Diclofenac works by inhibiting prostaglandin production, which is a major contributor to inflammation, discomfort, and fever. Diclofenac is rapidly and thoroughly absorbed from the gastrointestinal tract when taken with or after a meal. Peak plasma concentrations have obtained an average of 2 hours after consumption. At therapeutic doses, it binds to plasma proteins 99.7% of the time. Diclofenac is metabolized by the liver in a first-pass process.Clofenac Gel 20gm Dosage & Administration

Gel: Only for external use.2-4 g of Diclofenac gel should be applied to the skin 3-4 times daily, depending on the size of the area to be treated.The gel should be lightly rubbed into the affected area.Use on clean, dry skin. Avoid showering/bathing for at least 30 minutes after the gel/solution has dried.This gel may also be used in conjunction with other dosage forms of Diclofenac.After use, wash your hands. Avoid wearing clothing on your knees until the gel/solution has dried.ContraindicationsPatients who are allergic to any of the ingredients should avoid using them. Peptic ulcer, Diclofenac hypersensitivity, and other non-steroid anti-inflammatory agents. Diclofenac is also contraindicated in asthmatic patients who have had an attack of asthma, urticaria, or acute rhinitis caused by acetylsalicylic acid or other prostaglandin synthetase inhibitors. This Gel should not be used with occlusive airtight dressings.Side EffectsMost people tolerate Diclofenac Sodium well. Mild, infrequent, and transient side effects are quite common. During the first few days of treatment, patients may experience epigastric pain, eructation, nausea, and diarrhea, as well as dizziness or headache. These side effects are usually minor. Peripheral edema and skin reactions such as rash and dermatitis have also been reported. On the affected area, Diclofenac Sodium Gel can cause skin irritation, reddening, and a rash.Pregnancy & LactationDiclofenac should only be used if absolutely necessary during pregnancy. The smallest dose that is effective should be utilized. These medications are not advised to be taken during the first trimester of pregnancy. Diclofenac Sodium Gel is not suggested during pregnancy due to a lack of clinical evidence. Although a trace amount of Diclofenac may be discovered in breast milk, no adverse effects on the newborn are expected.Precautions & WarningsIn rare cases, patients using Diclofenac may develop peptic ulcers or experience gastrointestinal bleeding. Patients in their advanced years should be closely monitored. Diclofenac Sodium Gel should not be applied to the eyes or mucous membranes, and the hands should be thoroughly cleansed after application. It should not be consumed by mouth.Storage ConditionsStore in a cool and dry place, protected from light. Store below 30°C. Keep out of the reach of children.