Description:
Indications of Cotrim 60 ml Suspension
Cotrim 60 ml Suspension is bactericidal in vitro to a wide extend of Gram-positive and Gram-negative life forms, counting Streptococcus, Staphylococcus, Pneumococcus, Neisseria, B. catarrhalis, Escherichia coli, Klebsiella, Proteus spp., Haemophilus, Salmonella, Shigella, Vibrio cholerae, Brucella, Pneumocystis carinii, Nocardia and Bordetella. A especially tall degree of movement is displayed against Haemophilus influenzae, E. coli and Proteus spp., making Cotrimoxazole especially appropriate for the treatment of inveterate bronchitis and urinary tract contaminations. Cotrimoxazole applies its bactericidal activity by the successive bar of two bacterial protein frameworks within the biosynthesis of Folinic corrosive within the micro-organisms. The cooperative energy hence delivered accounts for the tall degree of bactericidal action.
Pharmacology of Cotrim 60 ml Suspension
Cotrimoxazole has a wide range of bactericidal actions against a wide extent of gram-positive & gram-negative microbes and a few protozoa. Co-trimoxazole containing Trimethoprim and Sulphamethoxazole in a 1:5 combination applies its bactericidal activity by the successive bar of two bacterial protein frameworks within the biosynthesis of folic corrosive within the microorganism.
Cotrim 60 ml Suspension Administration & Dosage
Cotrimoxazole double-strength tablet: Over 12 years
For mild to moderate infections: 1 tablet twice daily.
For severe infections: 1.5 tablets twice daily.
Long-term therapy (>14 days): 0.5 tablets twice daily.
Gonorrhea: 2 tablets every 12 hours for two days or 2.5 tablets followed by a further dose of 2.5 tablets after 8 hours.
Cotrimoxazole tablet: over 12 years
For mild to moderate infections: 2 tablets twice daily.
For severe infections: 2 tablets thrice daily.
Long term therapy: (>14 days): 1 tablet twice daily.
Cotrimoxazole suspension: Under 12 years
6-12 years: 2 teaspoonfuls twice daily.
6 month-5 years: 1 teaspoonful twice daily.
6 weeks-6 months: 0.5 teaspoonfuls twice daily.
Interaction
Touchiness to trimethoprim or sulphonamides. Patients with recorded megaloblastic weakness due to folate deficiency. Patients appearing stamped liver parenchymal harm, blood dyscrasia, extreme renal lacking, glucose 6-phosphate dehydrogenase insufficiency.
Contraindications
Touchiness to trimethoprim or sulphonamides. Patients with recorded megaloblastic weakness due to folate deficiency. Patients appearing checked for liver parenchymal harm, blood dyscrasia, serious renal inadequacy, and glucose 6-phosphate dehydrogenase lack.
Cotrim 60 ml Suspension Side Effect
The side impacts like crystalluria, unfavorably susceptible responses, hemolysis, thrombocytopenia, neutropenia, agranulocytosis, etc. have been detailed seldom with the Sulphamethoxazole-Trimethoprim combination. Other side impacts are less genuine in nature such as disquietude, cerebral pain, queasiness, and spewing. These are ordinarily temporal and don’t require the withdrawal of treatment.
Pregnancy & Lactation
The risks and benefits of treating a pregnant woman with Escitalopram during the third trimester should be carefully considered by the physician. It’s passed through human breast milk. The risk of citalopram exposure for the infant and the benefits of Escitalopram treatment should be considered when deciding whether to continue or stop nursing or Escitalopram therapy.
Precautions & Warnings
Touchiness to trimethoprim or sulphonamides. Patients with recorded megaloblastic weakness due to folate deficiency. Patients appearing checked for liver parenchymal harm, blood dyscrasia, serious renal inadequacy, and glucose 6-phosphate dehydrogenase lack.
Storage Conditions
Protect from light and moisture by storing below 30?C. Keep the medicine out of children’s reach.
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