Ezex Ointment

Indications of Ezex 25 Ointment

Clobetasone formulations are approved to treat atopic eczema, photodermatitis, otitis externa, primary irritant allergic dermatitis (including napkin rash), intertrigo, prurigo nodularis, seborrhoeic dermatitis, and insect bite responses. Clobetasone can be used as a maintenance treatment in between rounds of more potent topical steroids.

Pharmacology of Ezex 25 Ointment

Clobetasone Butyrate is a topically active corticosteroid with an excellent balance of activity and safety. It is more effective than 1 percent Hydrocortisone or the less active synthetic steroid formulations that are commonly used in the treatment of eczemas. It has minimal effect on the hypothalamic-pituitary-adrenal axis. If administered incorrectly, all topical corticosteroids can induce cutaneous atrophy. However, studies in animal and human models show that Clobetasone Butyrate produces less epidermal thinning than the other topical steroid examined.

Dosage & Administration of Ezex 25 Ointment

Apply to the affected area up to four times a day until improvement occurs, when the frequency of application may be reduced.

Interaction of Ezex 25 Ointment

There have been no reports of potentially harmful interactions. There have been no reports of potentially beneficial interactions.

Contraindications

In maternity (in high doses), Acute infections are present. Rosacea, leg ulcers, acne vulgaris, and widespread plaque psoriasis are all treated. 1-year-old child

Side Effects of Ezex 25 Ointment

Alterations in pigmentation and hypertrichosis; local atrophic changes Increased susceptibility to infection. Infections can be concealed. Adrenal insufficiency is a kind of acute adrenal insufficiency. Child growth retardation Symptoms of Cushing’s disease Amenorrhoea, hyperhidrosis, and skin thinning are all symptoms of amenorrhoea.

Pregnancy & Lactation

There is insufficient evidence on pregnancy safety in humans. Topical corticosteroid treatment in pregnant animals can result in embryonic development defects such as the cleft palate and intrauterine growth retardation. As a result, there is a very tiny chance of such consequences in the human fetus.

Precautions & Warnings

When administered topically to large regions, damaged skin, or beneath occlusive dressings, significant quantities may be absorbed to induce systemic effects. Peptic ulcers, osteoporosis, psychoses, or severe psychoneuroses are all possibilities. It should not be used indiscriminately to treat pruritus. CHF (cardiovascular disease) or hypertension (high blood pressure). Diabetes, epilepsy, glaucoma, infectious illnesses, ocular herpes simplex, chronic renal failure, and uremia are all possibilities. Tuberculosis, active or perhaps quiescent. Treatment of eye diseases on a local level. Elderly. Prolonged application to the face.

Storage Conditions

Store at temperatures below 30 degrees Celsius. Do not get paralyzed. Keep out of direct sunlight.