Neobet Cream (0.1%+0.5%)

Neobet is a combination medicine that is used to treat various types of skin infections. It minimizes symptoms of inflammation such as redness, swelling, and itching. It also has an antimicrobial action against the infection-causing microorganisms. Neobet is for external use only. Use it in the dose and duration as advised by the doctor. Do not apply it on an open wound and avoid getting it into your eyes or mouth. In case of accidental contact, rinse it with plenty of water. Use it regularly to get the most benefit of the medicine. Using $may cause few side effects like burning sensation and skin irritation. These are temporary and in most cases resolve with time. If the irritation persists or worsens, inform your doctor.

Introduction of Neomycin

Neobet is a combination medicine that is used to treat various types of skin infections. It minimizes symptoms of inflammation such as redness, swelling, and itching. It also has an antimicrobial action against the infection-causing microorganisms. Neobet is meant for external use only. It should be applied only to the affected area of the skin as per the dosage and schedule prescribed by your doctor. In order to get the most benefit, apply it regularly and preferably at a fixed time each day. Do not use larger amounts or apply it more often or for a longer duration than directed. This will only increase the risk of side effects. Avoid any contact with your eyes, nose or mouth. Rinse off any accidentally exposed area with water. Before using it, inform your doctor if you have any previous history of allergy to it or any other medicine. Pregnant or breastfeeding women should consult their doctor before using it. Local side effects like minor burning, stinging or irritation may be seen after the application of this medicine. These side effects are temporary and resolve quickly. Consult your doctor if these persist or if your condition does not improve.

Uses of Neobet

• Allergic conditions

Uses of Neobet

• Bacterial infections

Side effects of Neobet

Common

• Thinning of skin
• Increased risk of infection
• Weight gain
• Mood changes
• Behavioural changes

Side effects of Neobet

Common

• Application site reactions (burning, irritation, itching and redness)

How Neobet works

Neobet is a steroid which works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.

How Neobet works

Neobet is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.

Quick Tips

• Betamethasone can be taken with or without food, but try to have it at same time every day.
• Do not use it more often or for longer than advised by your doctor.
• Betamethasone can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.
• Side effects such as mood changes or stomach problems can happen when you start taking Betamethasone. Inform your doctor if this bothers you.
• Do not stop taking Betamethasone suddenly without talking to your doctor first as it may worsen your symptoms.
• You have been prescribed Neomycin for the treatment of bacterial skin infections.
• It should be applied to the affected areas as a thin film, two or three times daily, or as advised by your doctor.
• Don’t use it more often or for longer than advised by your doctor. Inform your doctor if your skin problem hasn’t improved after seven days of treatment.
• Don’t apply it to broken skin and avoid getting it in your eyes, nose or mouth.
• Don’t cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
• It may cause temporary burning, itching or a redness at application site. This is usually mild. Consult your doctor if you experience a more severe reaction.

Brief Description

Indication

Lichen planus, Psoriasis, Eczema, Contact dermatitis, Seborrhoeic dermatitis, Systemic lupus erythematosus, Lichen simplex, Prurigo nodularis

Adult Dose

Adult: Topical Apply 2-3 times/day. Usual duration: Up to 7 days/course.

Child Dose

Child: >2 yr: As cream/ointment: Apply onto the affected area(s) 2-3 times daily. Usual treatment duration: Up to 5 days/course.

Renal Dose

Renal impairment: Dose reduction may be necessary.

Contraindication

Hypersensitivity. Rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus and primary cutaneous viral infections. Not to be used in otitis externa complicated by ear-drum perforation. Treatment of primary infected skin lesions caused by fungi or bacteria; primary or secondary infections due to yeast; or secondary infections due to Pseudomonas or Proteus species.

Mode of Action

Betamethasone valerate is a corticosteroid which is effective in inflammatory dermatoses. It is also effective in less responsive conditions such as psoriasis. Neomycin sulfate is a broad spectrum antibiotic. It is bactericidal against many bacteria which are commonly associated with skin infections.

Precaution

Avoid prolonged treatment as it may lead to systemic corticosteroid effects even withour occlusion. Avoid prolonged excessive application to the facial areas. Withdraw treatment if there is spread of the infection. Risk of glaucoma development if preparation enters eye(s). Regular monitoring is recommended when used in psoriasis due to treatment tolerance, rebound relapses, generalised pustular psoriasis or systemic toxicity. Increased risk of contact sensitisation when used for extended period or recurrently. Pregnancy and lactation.

Side Effect

Prolonged use may cause local atrophic changes in the skin e.g. thining, striae and dilatation of superficial blood vessels. Local skin burning sensation, pruritus, pigmentation changes, allergic contact dermatitis and hypertrichosis. Ophthalmic preparation: Corneal ulceration, increased intraocular pressure, mydriasis, ptosis, epithelial punctate keratitis.

Interaction

If there is significant systemic absorption, neomycin sulfate may increase the respiratory depressant effects of neuromuscular blockers.