Povisep 6% Cream 25gm

Indications

Cream or ointment:
Therapeutically: As an adjunct to systemic therapy in the following indications-

Primary or secondary topical infections

Infected surgical incisions

Infected decubitus or stasis ulcers

Pyodermas

Secondarily infected dermatoses

Infected traumatic lesions

Solution:
 

For the prevention and treatment of surface infections as well as to degerm the skin, mucous membrane and hyperalimentation procedures

For seborrhea

For preoperative and postoperative scrubbing and washing of hospital operating room and equipments

For preoperative prepping of operative site, including the vagina

For disinfection of wounds, burns, lacerations and abrasions

As a prophylactic anti-infective agent in house, hospital & office procedures

Postoperative application to incisions to help prevent infection

In oral moniliasis (thrush); bacterial and mycotic skin infections, decubitus & stasis ulcers

As a preoperative swab in the mouth & throat

Gargle & Mouthwash: It is a pleasantly flavoured solution which is used:
 

For the treatment of acute mucosal infections of the mouth and pharynx.

For oral hygiene prior to, during and after dental and oral surgery.

Pharmacology

Povidone Iodine could be a complex of iodine and an natural polymer, povidone. This polymerization makes Povidone Iodine prevalent to conventional natural iodine. It draws out the germicidal action of iodine by liberating natural iodine gradually. Subsequently it includes a lower harmfulness than natural iodine. It gives rapid microbicidal action against both Gram-positive and Gram-negative microbes, protozoa, infections and fungi/yeasts. It is additionally sporicidal. It is the only microbicide with this wide range of action. It is non-staining, applies draw out germicidal activity and is additionally dynamic within the nearness of cleanser, blood, serum, discharge, mucosal discharges and water.

Administration & Dosage

Cream or ointment:

For the treatment of infection: Apply once or twice daily or at dressing changes for a maximum of 14 days.

For the prevention of infection: Apply once or twice a week for as long as necessary. The affected skin should be cleaned and dried and can be covered with a dressing or bandage.

Solution: Apply full strength as often as needed as paint, spray, or wet soak. Maybe bandaged (where necessary).

Gargle & Mouthwash: Adults and children over 6 years of age: Use undiluted or diluted with an equal volume of warm water. Gargle or rinse with up to 10 mL for up to 30 seconds without swallowing. Repeat up to four times daily, for up to 14 consecutive days, or as advised by the Registered Dental Surgeon/Physician.Surgical Scrub:

For Preoperative and Postoperative washing by Operating Personnel: Wet hands and forearms with water. Pour about 5 mL of Povidone Iodine Surgical Scrub on the palm of the hand and spread over both hands and forearms. Without adding more water, rub the Scrub thoroughly over all areas for about five minutes. Use a brush if desired. Clean thoroughly under fingernails. Add a little water and develop copious suds. Rinse thoroughly under running water. Complete the wash by scrubbing with another 5 mL of Povidone Iodine Surgical Scrub in the same way.

For Preoperative use on Patients: After the skin area is shaved, wet it with water. Apply Povidone Iodine Surgical Scrub (1 mL is sufficient to cover an area of 20-30 square inches), develop lather and scrub thoroughly for about five minutes. Rinse off by aid of sterile gauze saturated with water.

For use in the Physician’s Office: Use for washing whenever a germicidal soap is required.

Powder: Apply a light dusting of powder to the affected area. When dry, this forms a protective antiseptic layer over the area treated. Or use as advised by the Registered Physician. There are no special dosage recommendations for children or elderly patients.

Interaction

It exhibits interaction with strong alkali, sodium thiosulphate, sodium metabisulphite and thiomersal. Use with concurrent lithium therapy has been shown to exhibithypothyroidic effect.

Contraindications

It can cause extreme touchiness responses. Customary utilize in patients with thyroid disarranges (in specific nodular colloid goiter, endemic goiter and Hashimoto’s thyroiditis) or those getting lithium treatment is to be dodged. In seriously burnt patients serum iodide levels ought to be evaluated due to conceivable hepatic and renal disability. Povidone Iodine Powder ought to not be utilized in genuine cavities and in Children beneath the age of 2 a long time.

Side Effects

Povidone Iodine may cause hypersensitivity reactions and irritation of the skin and mucous membranes. The application of povidone Iodine to severe burns or to large areas otherwise denuded of skin may produce systemic adverse effects such as metabolic acidosis, hypernatraemia, and impairment of renal function. It may interfere with thyroid function tests.

Pregnancy & Lactation

Povidone Iodine Cream, Arrangement & Powder are not prescribed for utilize amid pregnancy since of the plausibility of retention of adequate iodine to influence the fetal thyroid. American Foundation of Pediatrics considers that the utilize of Povidone-Iodine is ordinarily consistent with breast bolstering. Counsel Enrolled Doctor. Customary utilize of Swish & Mouthwash and Surgical Clean ought to too be maintained a strategic distance from in pregnant and lactating ladies.

Precautions & Warnings

Cream or treatment: In case of profound or cut wounds or genuine burns, counsel Enrolled Doctor. On the off chance that redness, aggravation, swelling or torment endures or increments or in the event that disease happens, suspend utilize and counsel Enlisted Physician. Solution: In preoperative prepping, dodge ‘pooling’ underneath the understanding. Drawn out introduction to damp arrangement may cause bothering or seldom, extreme skin responses. In case of profound or cut wounds or genuine burns, counsel Enlisted Doctor. On the off chance that redness, bothering, swelling or torment continues or increments or in case disease happens, suspend utilize and counsel Enlisted Doctor.Gargle & Mouthwash: Regular use should be avoided as prolonged use may lead to the absorption of a significant amount of iodine. Do not use for more than 14 days. If sores or ulcers in the mouth do not heal within 14 days seek dental or medical advice. It is also not for use in children under 6 years of age. Regular use should be avoided in patients on concurrent lithium therapy.

Surgical Scrub: Special caution is needed when regular applications to broken skin are made to patients with pre-existing renal insufficiency. Regular use should be avoided in patients on concurrent lithium therapy. It can permanently discolor white gold jewellery and it is recommended that this type of jewellery should be removed before using this product.

Powder: Care must be taken when used on known iodine sensitivity, although do not normally react to Povidone-Iodine. Excess powder can be washed off readily with warm water. It should be used directly from the container. Not to be administered internally

Storage Conditions

Protect from light and moisture by storing below 30?C. Keep the medicine out of children’s reach.