Xylomet Plus Nasal Spray

Indications

This nasal spray is indicated for the prevention and treatment of allergic rhinitis (such as hay fever and perennial rhinitis) when it is accompanied by nasal congestion.

Pharmacology

Xylometazoline hydrochloride is a sympathomimetic with alphaadrenergic activity. It produces vasoconstriction thus relieving nasal congestion. This helps the patient with a cold to breathe more easily through the nose.

Sodium cromoglicate generally acts by a local effect on the nasal mucosa. It prevents the release of mediators of typel allergic reactions, including histamine and delayed anaphylaxis (SRSA) by sensitized mast cells after conjugation of antibiotics and antibodies. The drug does not inhibit the binding of IgE and specific antigens; instead, it prevents the release of substances (eg, histamine, SRSA) in response to this reaction. The drug also inhibits type III reactions (late allergies, Arthers) to a lesser extent.

Dosage 

Adults (including the elderly) and children: One spray each nostril four times daily.

Administration

How to use

Nasal spray Gently shake the bottle and remove the dust cover.

Place your index finger and middle finger on either side of the nozzle and place your thumb under the bottle. Press until a fine spray appears. If this is the first time you use it, or if you have not used it for a week or more, press the nasal applicator several times until a small amount of water comes out of the container.

Gently blow your nose to clear your nostrils.

Close one nostril and carefully insert the nasal applicator into the opened nostril. Tilt your head slightly forward and keep the spray upright. Inhale through your nose, and while inhaling, firmly press the white neck of the nasal applicator once to release the spray.

Exhale through your mouth.

Repeat the above steps in the same or another nostril for continuous administration.

 Cleansing:

The nasal spray cleanses at least once a week. The steps are as follows:

Remove the dust cover.

Gently pull down on the nasal applicator.

Clean applicator and dust cover with lukewarm water.

Shake off excess water and place in a normal place to dry. Avoid applying additional heat.

Gently push the applicator back to the top of the bottle and replace the dust cap.

Interaction

No information provided.

Contraindications

Contraindicated in patients with a known hypersensitivity to any ingredients of the preparation.

Side Effects

No serious side effects have been reported. Occasionally it can irritate the nasal mucosa on the first day of use. In rare cases, cromolyn sodium solution alone can reportedly cause wheezing and chest tightness. Due to the use of lower doses of xerometazoline in this preparation, it can cause mild side effects such as nasal irritation, dry nose, sneezing, headache, insomnia, drowsiness, and heart palpitations.

Pregnancy & Lactation

As with all medicines, caution should be exercised during pregnancy especially during the first trimester.

Precautions & Warnings

The prolonged use or abuse of decongestants in general may lead to rebound congestion or drug induced rhinitis.

Therapeutic Class

Mast Cell Stabiliser

Storage Conditions

Keep below 30?C temperature, away from light & moisture. Keep out of the reach of children.